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DURECT Corporation Invites You to Join Its Second Quarter 2005 Conference Call on the Web


CUPERTINO, Calif., July 8, 2005 /PRNewswire-FirstCall via COMTEX/ -- In conjunction with DURECT Corporation's (Nasdaq: DRRX) second quarter 2005 financial results press release, you are invited to listen to its conference call that will be broadcast live over the Internet on Friday, July 22, 2005 at 8:00 a.m. EDT.

What: DURECT Corporation's Second Quarter 2005 Earnings Conference Call

When: Friday, July 22nd, 2005, 8:00 a.m. EDT (5:00 a.m. PDT)

Where: www.durect.com and click "Investor Relations"

Live over the Internet -- Simply log on to the Web at the address listed above.

If you are unable to participate during the live webcast, the call will be archived on DURECT's website under Audio Archive in the "Investor Relations" section.

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company focused on the development of pharmaceutical systems based on its proprietary drug delivery platform technologies that treat chronic debilitating diseases and enable biotechnology products. These platform technologies include the SABER(TM) Delivery System (a patented and versatile depot injectable useful for protein and small molecule delivery), the ORADUR(TM) sustained release oral gel-cap technology (an oral sustained release technology with several potential abuse deterrent properties), the DURIN(TM) Biodegradable Implant (drug-loaded implant system), the TRANSDUR(TM) transdermal technology and the MICRODUR(TM) Biodegradable Microparticulates (microspheres injectable system). DURECT also collaborates with pharmaceutical companies to develop and commercialize proprietary and enhanced pharmaceutical products based on its technologies. DURECT has five disclosed on-going development programs of which four are in collaboration with pharmaceutical partners. Additional information about DURECT is available at www.durect.com.

NOTE: SABER(TM), ORADUR(TM), DURIN(TM), TRANSDUR(TM) and MICRODUR(TM) are trademarks of DURECT Corporation. Other referenced trademarks belong to their respective owners.

SOURCE DURECT Corporation

Schond L. Greenway, Executive Director, Investor Relations and Strategic Planning of DURECT Corporation, 408-777-1417

http://www.prnewswire.com