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DURECT Corporation Invites You to Join Its Phase II Trial Results Conference Call on the Web

CUPERTINO, Calif., Aug 24, 2001 /PRNewswire/ -- In conjunction with DURECT Corporation's (Nasdaq: DRRX) press release regarding Chronogesic(TM) Phase II clinical trial data, you are invited to listen to its conference call that will be broadcast live over the Internet on Wednesday, September 5, 2001 at 8:30 a.m. EDT with Jim Brown, President and Chief Executive Officer, Felix Theeuwes, Chairman and Chief Scientific Officer and Dennis Fisher, Vice President of Medical Affairs and Medical Director.

    What:   DURECT Corporation Chronogesic Phase II clinical trial data
            conference call
    When:   Wednesday, September 5, 2001, 8:30 a.m. EDT
    How:    Live over the Internet -- Simply log on to the Web
            at the address listed above or access through DURECT's Website.
DURECT Corporation is pioneering the development and commercialization of pharmaceutical systems that will deliver the right drug to the right site in the right amount at the right time. DURECT's pharmaceutical systems combine technology innovations from the medical device and drug delivery industries with proprietary pharmaceutical and biotechnology drug formulations. These capabilities can enable new drug therapies or optimize existing therapies based on a broad range of compounds, including small molecule pharmaceuticals as well as biotechnology molecules such as proteins, peptides and genes. Founded in 1998, the Company is headquartered in Cupertino, CA. The Company's World Wide Web site can be accessed at To join DURECT's email alert service, please register by selecting "Email Alerts" on the main Investor Relations web page at

If you are unable to participate during the live webcast, the call will be archived at:

Minimum Requirements to listen to broadcast: The RealPlayer software, downloadable free from, and at least a 14.4Kbps connection to the Internet. If you experience problems listening to the broadcast, send an email to

The statements in this press release regarding DURECT's products in development, product development plans, or expected product benefits, are forward-looking statements involving risks and uncertainties that could cause actual results to differ materially from those in such forward-looking statements. Potential risks and uncertainties include, but are not limited to, DURECT's ability to develop, manufacture and commercialize its products, successfully complete clinical trials, obtain product and manufacturing approvals from regulatory agencies, and validate and qualify a manufacturing facility, as well as marketplace acceptance of DURECT's products. Further information regarding these and other risks is included in the company's S-1 registration statement, filed with the SEC on September 22, 2000, 424(b) prospectus filed with the SEC on September 28, 2000, Quarterly Report on Form 10Q for the quarter ended June 30, 2001 filed with the SEC on August 14, 2001 and Annual Report on Form 10K for the fiscal year ended December 31, 2000 filed with the SEC on March 30, 2001.


CONTACT:          Schond L. Greenway at +1-408-777-1417 for DURECT Corporation